Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.72 |
| ▸ | HTR7 | P34969 | 8/20 | 0.72 |
| ▸ | HTR1A | P08908 | 6/20 | 0.72 |
| ▸ | HTR2A | P28223 | 6/20 | 0.72 |
| ▸ | HTR6 | P50406 | 6/20 | 0.72 |
| ▸ | DRD4 | P21917 | 3/20 | 0.72 |
| ▸ | DRD3 | P35462 | 3/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.72 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.72 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.72 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | HRH1 | P35367 | 1/20 | 0.72 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.72 |
| ▸ | HTR5A | P47898 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fananserin SCHEMBL340722 | 0.83 | HTR7 (1.00) | DRD2HTR7HTR1AHTR2AHTR6 | |
| Fananserin SCHEMBL5779774 | 0.83 | HTR7 (1.00) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL9726216 | 0.79 | HTR2A (0.56) | HTR7HTR2AHTR6HTR2C | |
| SCHEMBL6991546 | 0.79 | DRD2 (0.54) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL9757700 | 0.77 | HTR7 (0.73) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL6996766 | 0.77 | DRD2 (0.54) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL7000579 | 0.77 | DRD2 (0.53) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL7000574 | 0.77 | DRD2 (0.53) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL9757519 | 0.75 | HTR7 (0.95) | DRD2HTR7HTR1AHTR2AHTR6 | |
| SCHEMBL6999498 | 0.74 | HTR1A (0.55) | DRD2HTR7HTR1AHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |