Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | ESR1 | P03372 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28622229 | 0.98 | LMNA (0.75) | LMNAALDH1A1TSHRTDP1ESR1 | |
| SCHEMBL1995221 | 0.98 | LMNA (0.75) | LMNAALDH1A1TSHRTDP1ESR1 | |
| Butanedione SCHEMBL28991330 | 0.93 | LMNA (0.68) | LMNAALDH1A1TSHRTDP1ESR1 | |
| SCHEMBL27647501 | 0.92 | ALDH1A1 (0.81) | LMNAALDH1A1TSHRTDP1ESR1 | |
| Propylparaben SCHEMBL1078677 | 0.91 | ESR1 (0.86) | LMNAALDH1A1TSHRTDP1ESR1 | |
| Benzoic Acid SCHEMBL29000838 | 0.91 | LMNA (0.89) | LMNAALDH1A1TSHRTDP1ESR1 | |
| SCHEMBL49950 | 0.90 | ALDH1A1 (0.84) | LMNAALDH1A1TSHRTDP1ESR1 | |
| Propylparaben SCHEMBL28614294 | 0.90 | ESR1 (0.83) | LMNAALDH1A1TSHRTDP1ESR1 | |
| SCHEMBL9726256 | 0.89 | TSHR (0.72) | LMNAALDH1A1TSHRTDP1ESR1 | |
| SCHEMBL28758641 | 0.88 | ALDH1A1 (0.81) | LMNAALDH1A1TSHRTDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5078907-A | UNSYMMETRICAL DICARBOXYLIC ESTERS AS BLEACH PRECURSORS | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0426217-A2 | Bleach precursors | UNILEVER N.V. (NL) | 1991-05-08 | — | — | EP | disclosed |