Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726302 | 0.91 | L3MBTL1 (0.42) | ALDH1A1KDM4EMAPTGLAPOLB | |
| SCHEMBL9726388 | 0.85 | KDM4E (0.41) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL9726327 | 0.82 | KDM4E (0.39) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL6731647 | 0.82 | ADORA3 (0.41) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL10688342 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL9726407 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL9726329 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL28845147 | 0.80 | ADORA3 (0.41) | ALDH1A1KDM4EMAPTPOLBL3MBTL1 | |
| SCHEMBL3591480 | 0.79 | POLB (0.38) | ALDH1A1KDM4EMAPTGLAPOLB | |
| SCHEMBL9830074 | 0.78 | KDM5B (0.34) | MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142055-A | Dehydrofluorinating reduced fluoroalkyl pyridine compound | MONSANTO COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| US-4978384-A | HERBICIDES | MONSANTO COMPANY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4826530-A | PREEEMERGENCE AND SELECTIVE POSTEMEREGENCE HERBICIDES | MONSANTO COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| US-4692184-A | HERBICIDES | MONSANTO COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0133612-A2 | Substituted 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1985-02-27 | — | — | EP | disclosed |