Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726388 | 0.86 | KDM4E (0.41) | IGF1RKDM4EMAPTPOLBKMT2A | |
| SCHEMBL10688342 | 0.83 | KDM4E (0.44) | SMN1; SMN2KDM4EMAPTPOLBKMT2A | |
| SCHEMBL9726327 | 0.83 | KDM4E (0.39) | KDM4EMAPTPOLBKMT2AADORA3 | |
| SCHEMBL6731647 | 0.83 | ADORA3 (0.41) | SMN1; SMN2KDM4EMAPTPOLBKMT2A | |
| SCHEMBL9726407 | 0.82 | KDM4E (0.41) | SMN1; SMN2KDM4EMAPTPOLBKMT2A | |
| SCHEMBL28845147 | 0.81 | ADORA3 (0.41) | SMN1; SMN2KDM4EMAPTPOLBKMT2A | |
| SCHEMBL9726274 | 0.80 | ALDH1A1 (0.39) | KDM4EMAPTPOLBKMT2AADORA3 | |
| SCHEMBL9726370 | 0.79 | KDM4E (0.40) | SMN1; SMN2KDM4EMAPTPOLBKMT2A | |
| SCHEMBL9726286 | 0.79 | KDM4E (0.40) | KDM4EMAPTPOLBKMT2AADORA3 | |
| SCHEMBL9726378 | 0.79 | KDM4E (0.48) | SMN1; SMN2KDM4EMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142055-A | Dehydrofluorinating reduced fluoroalkyl pyridine compound | MONSANTO COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| US-4978384-A | HERBICIDES | MONSANTO COMPANY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4826530-A | PREEEMERGENCE AND SELECTIVE POSTEMEREGENCE HERBICIDES | MONSANTO COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| US-4692184-A | HERBICIDES | MONSANTO COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0133612-A2 | Substituted 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1985-02-27 | — | — | EP | disclosed |