Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726284 | 0.83 | KDM4E (0.62) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL9726323 | 0.81 | ADORA2B (0.50) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL10509439 | 0.81 | ADORA2B (0.50) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL6028459 | 0.79 | EGFR (0.58) | ADORA2BKDM4EALDH1A1HTTGAA | |
| SCHEMBL9726271 | 0.78 | ALDH1A1 (0.64) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL9726351 | 0.78 | ADORA2B (0.45) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL10507556 | 0.78 | ADORA2B (0.48) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL9726279 | 0.77 | ADORA2B (0.47) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL10507774 | 0.76 | ADORA2B (0.46) | ADORA2BLMNAKDM4EALDH1A1HTT | |
| SCHEMBL10508024 | 0.76 | ADORA2B (0.46) | ADORA2BLMNAKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142055-A | Dehydrofluorinating reduced fluoroalkyl pyridine compound | MONSANTO COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0133612-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | MONSANTO COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4978384-A | HERBICIDES | MONSANTO COMPANY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4826530-A | PREEEMERGENCE AND SELECTIVE POSTEMEREGENCE HERBICIDES | MONSANTO COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| US-4692184-A | HERBICIDES | MONSANTO COMPANY (US) | 1987-09-08 | — | — | US | disclosed |