Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | MMP13 | P45452 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788580 | 0.88 | TSHR (0.67) | ALDH1A1SMN1; SMN2HPGDLMNAPOLB | |
| SCHEMBL29194733 | 0.87 | SMN1; SMN2 (0.59) | ALDH1A1MMP13SMN1; SMN2HTTHPGD | |
| SCHEMBL20457819 | 0.86 | TSHR (0.66) | SMN1; SMN2LMNAPOLBTSHRKDM4E | |
| SCHEMBL792125 | 0.86 | GLA (0.70) | ALDH1A1POLBKMT2A | |
| SCHEMBL26616786 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MMP13SMN1; SMN2HTTHPGD | |
| SCHEMBL30633848 | 0.85 | ALDH1A1 (0.67) | ALDH1A1MMP13SMN1; SMN2HTTHPGD | |
| SCHEMBL2931410 | 0.84 | MMP13 (0.70) | ALDH1A1MMP13SMN1; SMN2HTTHPGD | |
| SCHEMBL28540163 | 0.83 | TSHR (0.61) | SMN1; SMN2LMNAPOLBTSHRKDM4E | |
| SCHEMBL13181425 | 0.83 | TSHR (0.61) | SMN1; SMN2LMNAPOLBTSHRKDM4E | |
| SCHEMBL3815151 | 0.83 | ALDH1A1 (0.72) | ALDH1A1MMP13SMN1; SMN2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |