SCHEMBL9726568

SCHEMBL9726568

COc1ccc(C(=O)c2c(C)cc(C)cc2C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.55
KMT2A Q03164 3/20 0.55
NPSR1 Q6W5P4 3/20 0.55
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 2/20 0.55
LMNA P02545 2/20 0.55
MAPT P10636 2/20 0.55
MAPK1 P28482 1/20 0.55
RAB9A P51151 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
GAA P10253 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MCOLN3 Q8TDD5 1/20 0.54
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
RAPGEF4 Q8WZA2 1/20 0.53
NPC1 O15118 1/20 0.53
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28006246 0.87 HPGD (0.56) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL28274214 0.86 KMT2A (0.67) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL26417906 0.86 MAPT (0.51) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL28242772 0.84 KMT2A (0.65) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL7481917 0.84 ALDH1A1 (0.62) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL15686208 0.83 TUBB4A (0.64) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL15760640 0.83 KMT2A (0.56) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL9857167 0.82 NPC1 (0.63) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL28998063 0.82 HPGD (0.51) HPGDKMT2ANPSR1ALDH1A1MEN1
SCHEMBL9856924 0.82 ALDH1A1 (0.65) HPGDKMT2ANPSR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121086653-B Long-service-life anti-fouling coating for panel of photovoltaic module and preparation method thereof 上海品诚控股集团有限公司 2026-02-27 CN disclosed
US-5110940-A Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase BRISTOL-MYERS COMPANY (US) 1992-05-05 US disclosed
US-5068346-A Anticholesterol agents BRISTOL-MYERS COMPANY (US) 1991-11-26 US disclosed
US-4897490-A DERIVATIVES OF BETA-HYDROXY,OMEGA-DIPHENYL,TETRAZOL-5-YL ALK-OMEGA-ENOIC ACID, ESTER OR LACTONE BRISTOL-MEYERS COMPANY (US) 1990-01-30 US disclosed
WO-1988006584-A1 ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS BRISTOL-MYERS COMPANY (US) 1988-09-07 WO disclosed