Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28274214 | 0.95 | KMT2A (0.67) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL28242772 | 0.93 | KMT2A (0.65) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL3288949 | 0.90 | LMNA (0.59) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| Bicarbonate SCHEMBL2149155 | 0.89 | LMNA (0.57) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11495001 | 0.88 | LMNA (0.56) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10988695 | 0.87 | SRD5A2 (0.63) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9726573 | 0.85 | KMT2A (0.57) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7264522 | 0.85 | HPGD (0.57) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL50648 | 0.84 | KMT2A (0.56) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 | |
| Formic Acid SCHEMBL2149150 | 0.84 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
| US-10538509-B2 | Decarboxylative cross-coupling and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-01-21 | — | — | US | disclosed |
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| WO-2015153381-A2 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-10-08 | — | — | WO | disclosed |
| EP-0426846-A1 | FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4054682-A | COATINGS, PRINTING INKS | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | ALDH1A1 149/4885LMNA 4743/4885KMT2A 1610/4885 |
| US-10538509-B2 | Decarboxylative cross-coupling and applications thereof | PPOX, DDC, DDO | ALDH1A1 130/4885LMNA 4676/4885KMT2A 1237/4885 |
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | ALDH1A1 149/4885LMNA 4743/4885KMT2A 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.