Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96647 | 0.93 | MAOA (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4957180 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL6577458 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL6577459 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL11834546 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL1772170 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL6577425 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL98283 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL6579084 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT | |
| SCHEMBL6577351 | 0.91 | MAPT (0.53) | HDAC1HDAC2SIGMAR1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4087 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063666-B | Multifunctional polyester material and preparation method and application thereof | 四川大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117126153-A | New coronavirus inhibitor, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-11-28 | — | — | CN | claimed |
| CN-116063666-A | Multifunctional polyester material and preparation method and application thereof | 四川大学 | 2023-05-05 | — | — | CN | claimed |
| US-11622994-B2 | Therapy for vitiligo | CLINUVEL PHARMACEUTICALS LIMITED (AU) | 2023-04-11 | — | — | US | claimed |
| CN-113444005-A | Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin | 四川大学 | 2021-09-28 | — | — | CN | claimed |
| CN-112043724-A | Application of arsenic-containing compound | 常州高新技术产业开发区三维工业技术研究所有限公司 | 2020-12-08 | — | — | CN | claimed |
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| US-20200108159-A1 | RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R | WAKE FOREST UNIVERSITY | 2020-04-09 | — | — | US | claimed |
| EP-0255082-A2 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | claimed |
| EP-0239874-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-07 | — | — | EP | claimed |
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4010193-A | (ALKYLAMINO)ALKYL SUBSTITUTED BENZOATES, LOCAL ANESTHETIC, ANTIFIBRILLATORY, ANTIARRHYTHMIAL | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1977-03-01 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |