SCHEMBL98283

SCHEMBL98283

O=[C]CCCCCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
SIGMAR1 Q99720 9/20 0.52
MAOA P21397 1/20 0.50
NAAA Q02083 3/20 0.48
MIF P14174 1/20 0.48
MAOB P27338 1/20 0.48
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47
ALOX5 P09917 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6577425 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6577459 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6577351 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL11834546 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL4957180 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6579084 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6577458 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL1772170 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL96647 0.98 MAOA (0.52) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL97266 0.91 HDAC3 (0.50) MAPTRXFP1SIGMAR1MAOAMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063666-B Multifunctional polyester material and preparation method and application thereof 四川大学 2024-04-19 CN claimed
CN-116063666-A Multifunctional polyester material and preparation method and application thereof 四川大学 2023-05-05 CN claimed
CN-113444005-A Method for synthesizing novel glutaric acid compound from diaryl substituted non-activated olefin 四川大学 2021-09-28 CN claimed
WO-2009026422-A2 TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS ABBOTT LABORATORIES (US) 2009-02-26 WO claimed
US-6875740-B1 Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2005-04-05 US claimed
US-5541303-A 3,4'-dideoxymycaminosltylonolide derivative and process for producing the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1996-07-30 US claimed
CN-116063666-B Multifunctional polyester material and preparation method and application thereof 四川大学 2024-04-19 CN disclosed
US-20240084308-A1 FIBROTIC TREATMENT MONASH UNIVERSITY (AU) 2024-03-14 US disclosed
US-20240034845-A1 POLYMER PARTICLES QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2024-02-01 US disclosed
EP-3384549-B1 SODIUM-ION ELECTROLYTE COMPOSITION UNIV DEAKIN (AU) 2024-01-17 EP disclosed
US-11834663-B2 Fibrotic treatment MONASH UNIVERSITY (AU) 2023-12-05 US disclosed
US-20230348674-A1 HYDROGELS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-11-02 US disclosed
WO-2023190111-A1 RAFT POLYMERIZATION REACTION SOLUTION AND RAFT POLYMERIZATION REACTION SOLUTION PRODUCTION METHOD テクノUMG株式会社 2023-10-05 WO disclosed
EP-0030630-A2 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-06-24 EP disclosed
EP-0029557-A2 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-06-03 EP disclosed
EP-0010667-A1 Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-05-14 EP disclosed
US-4088537-A BIOTRANSFORMATION THE UPJOHN COMPANY (US) 1978-05-09 US disclosed
US-4041055-A SULFENYLATION, MICHAEL ADDITION, REACTION WITH THIOPHILE, HYDROLYSIS THE UPJOHN COMPANY (US) 1977-08-09 US disclosed
US-3975532-A ANALGESIC ICI UNITED STATES INC. (US) 1976-08-17 US disclosed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834663-B2 Fibrotic treatment MMP1, ENPEP, RNPEP MAPT 3950/4885RXFP1 103/4885SIGMAR1 4840/4885
US-20230348674-A1 HYDROGELS PHYKPL, TST, PHOSPHO1 MAPT 3246/4885RXFP1 3700/4885SIGMAR1 1231/4885
US-20240084308-A1 FIBROTIC TREATMENT MMP1, ENPEP, RNPEP MAPT 3950/4885RXFP1 103/4885SIGMAR1 4840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.