SCHEMBL1772170

SCHEMBL1772170

O=[C]CCCCCCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
SIGMAR1 Q99720 9/20 0.52
MAOA P21397 1/20 0.50
NAAA Q02083 3/20 0.48
MIF P14174 1/20 0.48
MAOB P27338 1/20 0.48
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47
ALOX5 P09917 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6577425 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6577459 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL98283 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6577351 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL11834546 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL4957180 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6579084 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL6577458 1.00 MAPT (0.53) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL96647 0.98 MAOA (0.52) MAPTRXFP1SIGMAR1MAOANAAA
SCHEMBL97266 0.91 HDAC3 (0.50) MAPTRXFP1SIGMAR1MAOAMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP disclosed
CN-114466667-A Method for reducing malodorous smells using cucurbituril 爱客多有限公司 2022-05-10 CN disclosed
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-10626095-B2 Cyanotriazole compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-04-21 US disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-20160229816-A1 CYANOTRIAZOLE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2016-08-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
EP-3022199-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2016-05-25 EP disclosed
US-20160015786-A1 MOBILIZING AGENTS AND USES THEREFOR MATER MEDICAL RESEARCH INSTITUTE LIMITED (AU) 2016-01-21 US disclosed
EP-2961398-A1 MOBILIZING AGENTS AND USES THEREFOR Mater Medical Research Institute Limited (AU) 2016-01-06 EP disclosed
US-7108879-B2 Process for improving the durability of, and/or stabilizing, microbially perishable products SCHUR JORG PETER 2006-09-19 US disclosed
EP-0856007-B1 CYCLOPEPTIDE DERIVATIVES MERCK PATENT GMBH (DE) 2004-04-21 EP disclosed
US-6566491-B2 Used as integrin inhibitors, in particular for the prevention and treatment of circulatory diseases, thrombosis, heart infarct, coronary heart diseases, arteriosclerosis, angiogenic diseases and in tumor therapy. MERCK PATENT GESELLSCHAFT (DE) 2003-05-20 US disclosed
US-6514551-B1 Adjuvant comprising microbicidally active flavoring agent; cutting agent which comprises an antimicrobial composition of benzyl alcohol, flavoring polyphenol and a vegetable oil SCHUR JORG PETER (DE) 2003-02-04 US disclosed
US-20020032306-A1 CYCLOPEPTIDE DERIVATIVES BIOMET DEUTSCHLAND GMBH (DE) 2002-03-14 US disclosed
EP-1167375-A1 ERYTHROMYCIN DERIVATIVES HOKURIKU SEIYAKU CO., LTD. (JP) 2002-01-02 EP disclosed
WO-2000012492-A1 BENZOXAZINE DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-09 WO disclosed
US-5948812-A ORDORANTS GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 1999-09-07 US disclosed
EP-0856007-A1 CYCLOPEPTIDE DERIVATIVES MERCK PATENT GmbH (DE) 1998-08-05 EP disclosed
WO-1997014716-A1 CYCLOPEPTIDE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1997-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626095-B2 Cyanotriazole compounds CS, PC, ACAT1 MAPT 2196/4885RXFP1 2555/4885SIGMAR1 4091/4885
US-20020032306-A1 CYCLOPEPTIDE DERIVATIVES CORO1C, CYCS, CORO1A MAPT 4254/4885RXFP1 175/4885SIGMAR1 2226/4885
US-20160015786-A1 MOBILIZING AGENTS AND USES THEREFOR HIF1AN, CXCL12, HIF1A MAPT 4873/4885RXFP1 1122/4885SIGMAR1 4365/4885
US-20160229816-A1 CYANOTRIAZOLE COMPOUNDS CS, PC, ACAT1 MAPT 2196/4885RXFP1 2555/4885SIGMAR1 4091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.