Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726435 | 0.88 | TSHR (0.48) | TSHREPHX2ALDH1A1LMNACA12 | |
| SCHEMBL26478859 | 0.81 | ZDHHC20 (0.56) | TSHREPHX2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL23030243 | 0.79 | TSHR (0.45) | TSHREPHX2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17722840 | 0.78 | ALDH1A1 (0.54) | TSHREPHX2ALDH1A1LMNA | |
| SCHEMBL9726453 | 0.78 | PRMT1 (0.48) | TSHREPHX2ALDH1A1LMNA | |
| SCHEMBL2612181 | 0.76 | ZDHHC20 (0.59) | TSHREPHX2ALDH1A1LMNARECQL | |
| SCHEMBL407248 | 0.75 | TSHR (0.61) | TSHREPHX2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9726698 | 0.75 | TET2 (0.50) | TSHREPHX2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21538522 | 0.75 | TSHR (0.61) | TSHREPHX2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4103840 | 0.74 | TSHR (0.54) | TSHREPHX2ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |