Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726421 | 0.86 | ECE1 (0.45) | PRMT1ADRA1AKDM4EL3MBTL1LMNA | |
| SCHEMBL38788 | 0.78 | ZDHHC20 (0.57) | PRMT1ADRA1AMAPTMEN1KMT2A | |
| SCHEMBL9726624 | 0.78 | TSHR (0.52) | ALDH1A1LMNAEPHX2TSHR | |
| SCHEMBL3900089 | 0.77 | ALDH1A1 (0.56) | PRMT1ADRA1AMAPTMEN1KMT2A | |
| SCHEMBL3900092 | 0.77 | ALDH1A1 (0.56) | PRMT1ADRA1AMAPTMEN1KMT2A | |
| SCHEMBL18666797 | 0.76 | PRMT1 (0.42) | PRMT1ADRA1AMAPTMEN1KMT2A | |
| SCHEMBL28459307 | 0.75 | KMT2A (0.49) | PRMT1ADRA1AMAPTMEN1KMT2A | |
| SCHEMBL20657261 | 0.75 | KMT2A (0.49) | PRMT1ADRA1AMAPTMEN1KMT2A | |
| SCHEMBL20577970 | 0.75 | PLA2G4A (0.47) | PRMT1ADRA1AMAPTMEN1KMT2A | |
| SCHEMBL31475480 | 0.74 | PRMT1 (0.81) | PRMT1ADRA1ALMNASLC22A6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |