Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315699 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10LPAR1 | |
| SCHEMBL6151978 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10LPAR1 | |
| SCHEMBL11138432 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10LPAR1 | |
| SCHEMBL27974766 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10LPAR1 | |
| SCHEMBL8782258 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10LPAR1 | |
| SCHEMBL3628413 | 0.76 | SMN1; SMN2 (0.61) | ALDH1A1KDM4EHPGDPOLBTP53 | |
| SCHEMBL707627 | 0.76 | CTNNB1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10LPAR1 | |
| SCHEMBL20346750 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10LPAR1 | |
| SCHEMBL8972334 | 0.75 | MYC (0.50) | ALDH1A1KDM4EHPGDHSD17B10FFAR1 | |
| SCHEMBL30675634 | 0.72 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875745-B2 | {1-[(2S,3S)-2-(2,3-dihydro-1H-inden-2-ylmethyl)-3-(3,5-dimethoxy-4- methylphenyl)-3-hydroxylpropyl]-1H-pyrrol-3-yl}acetic acid; for urinary system disease selected from the group of prostatic hypertrophy, neurogenic bladder dysfunction disease, dysuria, pollakiuria, night urination and urodynia | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-25 | — | — | US | disclosed |
| US-20070149595-A1 | Compounds having lysophosphatidic acid receptor antagonism and uses thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149595-A1 | Compounds having lysophosphatidic acid receptor antagonism and uses thereof | LPAR2, LPAR1, LPAR5 | ALDH1A1 4013/4885KDM4E 2929/4885HPGD 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.