Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726917 | 0.85 | ACHE (0.39) | ACHESMN1; SMN2HPGDALDH1A1MAPK1 | |
| SCHEMBL9726813 | 0.78 | SMN1; SMN2 (0.42) | ACHESMN1; SMN2HPGDALDH1A1MAPK1 | |
| SCHEMBL8345539 | 0.78 | ALDH1A1 (0.52) | ACHESMN1; SMN2HPGDALDH1A1MAPK1 | |
| SCHEMBL9726921 | 0.74 | SMN1; SMN2 (0.42) | ACHESMN1; SMN2ALDH1A1KDM4EMAOB | |
| SCHEMBL8345919 | 0.74 | HTT (0.41) | ACHESMN1; SMN2HPGDALDH1A1MAPK1 | |
| SCHEMBL28126467 | 0.74 | MAPT (0.44) | SMN1; SMN2HPGDALDH1A1HSD17B1LMNA | |
| SCHEMBL9730784 | 0.67 | RXRB (0.47) | ACHEHPGDALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28515999 | 0.67 | ALDH1A1 (0.55) | SMN1; SMN2HPGDALDH1A1MAPK1CYP3A4 | |
| SCHEMBL1821844 | 0.66 | PBRM1 (0.45) | SMN1; SMN2HPGDALDH1A1CYP3A4KDM4E | |
| SCHEMBL11910715 | 0.66 | HPGD (0.50) | ACHESMN1; SMN2HPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081271-A | Differentiation-inducing agent for neoplastic cells; therapeutic agent for psoriasis or immune and inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |