Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726921 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL9730784 | 0.84 | RXRB (0.47) | ACHEHPGDALDH1A1KDM4ERXRA | |
| SCHEMBL9716881 | 0.82 | ACHE (0.39) | SMN1; SMN2ACHEHPGDALDH1A1NPC1 | |
| SCHEMBL9716901 | 0.81 | ACHE (0.38) | ACHEHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8345539 | 0.80 | ALDH1A1 (0.52) | SMN1; SMN2ACHEHPGDALDH1A1CYP3A4 | |
| SCHEMBL9726808 | 0.78 | ACHE (0.39) | SMN1; SMN2ACHEHPGDALDH1A1CYP3A4 | |
| SCHEMBL8345919 | 0.76 | HTT (0.41) | SMN1; SMN2ACHEHPGDALDH1A1CYP3A4 | |
| SCHEMBL9726917 | 0.74 | ACHE (0.39) | SMN1; SMN2ACHEHPGDALDH1A1CYP3A4 | |
| SCHEMBL5012568 | 0.74 | ACHE (0.33) | ACHEHPGDNPC1RAB9A | |
| SCHEMBL29381894 | 0.74 | KMT2A (0.51) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081271-A | Differentiation-inducing agent for neoplastic cells; therapeutic agent for psoriasis or immune and inflammatory diseases | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |