Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.41 |
| ▸ | USP2 | O75604 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726950 | 0.85 | GRIN1 (0.43) | MEN1KMT2ACYP2D6CYP3A4USP2 | |
| SCHEMBL13483585 | 0.69 | HSD11B1 (0.44) | KMT2ACYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL6580284 | 0.68 | CYP3A4 (0.47) | MEN1KMT2ACYP2D6CYP3A4OPRM1 | |
| SCHEMBL17360649 | 0.67 | KMT2A (0.41) | MEN1KMT2ACYP2D6ALOX15OPRM1 | |
| SCHEMBL5563143 | 0.66 | KMT2A (0.48) | MEN1KMT2ACYP2D6CYP3A4USP2 | |
| SCHEMBL5597469 | 0.66 | RAB9A (0.43) | MEN1KMT2ACYP2D6CYP3A4USP2 | |
| SCHEMBL9726979 | 0.66 | KMT2A (1.00) | MEN1KMT2ACYP2D6CYP3A4OPRM1 | |
| SCHEMBL769875 | 0.64 | HSD11B1 (0.46) | KMT2ACYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL373948 | 0.64 | HSD11B1 (0.46) | KMT2ACYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL19347151 | 0.64 | KMT2A (0.46) | MEN1KMT2ACYP2D6CYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128466-A | For monitoring lithium levels in patients receiving lithium treatment for depression | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1992-07-07 | — | — | US | disclosed |