Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727141 | 0.87 | MAPT (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL9727191 | 0.84 | PDE4B (0.41) | PDE4BPDE4DCYP1A2 | |
| SCHEMBL9132364 | 0.76 | FEN1 (0.50) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL9130384 | 0.73 | FEN1 (0.47) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL10377175 | 0.73 | FEN1 (0.47) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL9352322 | 0.73 | FEN1 (0.47) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL9131042 | 0.72 | PTGDR2 (0.46) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL9628997 | 0.72 | FEN1 (0.45) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL9131517 | 0.72 | FEN1 (0.45) | PDE4APDE4BPDE4CPDE4DFEN1 | |
| SCHEMBL10377453 | 0.71 | FEN1 (0.43) | PDE4APDE4BPDE4CPDE4DFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126352-A | Antiallergy, antiinflammatory, antiulcer, hypotensive, antibody inhibitors | SCHERING CORPORATION (US) | 1992-06-30 | — | — | US | claimed |