Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 3/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PKD1 | P98161 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726994 | 0.87 | PDE4A (0.47) | CYP1A2CYP2C19ALDH1A1PDE4BPDE4D | |
| SCHEMBL9727191 | 0.85 | PDE4B (0.41) | MAPTCYP1A2TP53PDE4BPDE4D | |
| SCHEMBL6009928 | 0.79 | MAPT (0.49) | MAPTMEN1CYP1A2HPGDCYP2C19 | |
| SCHEMBL30438257 | 0.79 | MAPT (0.49) | MAPTMEN1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9628931 | 0.76 | MAPT (0.46) | MAPTMEN1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9132031 | 0.76 | MAPT (0.44) | MAPTMEN1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9132455 | 0.76 | MAPT (0.48) | MAPTMEN1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9131645 | 0.75 | MAPT (0.43) | MAPTMEN1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9129169 | 0.75 | BAZ2B (0.45) | MAPTMEN1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9799505 | 0.75 | MEN1 (0.47) | MAPTMEN1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126352-A | Antiallergy, antiinflammatory, antiulcer, hypotensive, antibody inhibitors | SCHERING CORPORATION (US) | 1992-06-30 | — | — | US | claimed |