Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727141 | 0.85 | MAPT (0.46) | PDE4BPDE4DHTR6CYP1A2DRD2 | |
| SCHEMBL9726994 | 0.84 | PDE4A (0.47) | PDE4BPDE4DCYP1A2 | |
| SCHEMBL10658791 | 0.78 | PDE4B (0.42) | PDE4BPDE4DHTR6CYP1A2TRPV1 | |
| SCHEMBL9761878 | 0.77 | KCNK3 (0.50) | PDE4BPDE4DTRPV1NPY5RPPARG | |
| SCHEMBL10660631 | 0.76 | PDE4B (0.42) | PDE4BPDE4DHTR6CYP1A2TRPV1 | |
| SCHEMBL10655441 | 0.72 | PDE4B (0.42) | PDE4BPDE4DCYP1A2TRPV1NPY5R | |
| SCHEMBL5871981 | 0.71 | GAA (0.50) | PDE4BPDE4DHTR6CYP1A2TRPV1 | |
| SCHEMBL4194695 | 0.71 | PDE4B (0.47) | PDE4BPDE4DCYP1A2TRPV1NPY5R | |
| SCHEMBL4342841 | 0.71 | TP53 (0.45) | PDE4BPDE4DHTR6CYP1A2TRPV1 | |
| SCHEMBL29425535 | 0.71 | CTSK (0.52) | PDE4BPDE4DCYP1A2TRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126352-A | Antiallergy, antiinflammatory, antiulcer, hypotensive, antibody inhibitors | SCHERING CORPORATION (US) | 1992-06-30 | — | — | US | claimed |