Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 6/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799482 | 0.86 | MAPT (0.43) | MEN1KMT2ACYP1A2MAPTHPGD | |
| SCHEMBL9799632 | 0.85 | FEN1 (0.50) | MAPTHPGDCYP2C19ALDH1A1PDE4A | |
| SCHEMBL9799483 | 0.84 | PDE4A (0.46) | MEN1KMT2ACYP1A2MAPTHPGD | |
| SCHEMBL9535601 | 0.82 | MAPT (0.50) | MEN1KMT2ACYP1A2MAPTHPGD | |
| SCHEMBL9799534 | 0.79 | MAPT (0.50) | MEN1KMT2ACYP1A2MAPTHPGD | |
| SCHEMBL10379090 | 0.78 | MAPT (0.46) | MEN1KMT2ACYP1A2MAPTHPGD | |
| SCHEMBL9629146 | 0.78 | MAPT (0.49) | MEN1KMT2ACYP1A2MAPTHPGD | |
| SCHEMBL9799715 | 0.77 | ALDH1A1 (0.47) | KMT2ACYP1A2MAPTCYP2C19ALDH1A1 | |
| SCHEMBL10377111 | 0.76 | MAPT (0.47) | MEN1KMT2ACYP1A2MAPTHPGD | |
| SCHEMBL9628920 | 0.76 | MAPT (0.46) | MEN1KMT2ACYP1A2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996212-A | Antiinflammatory and anti-hyperproliferative compounds | SCHERING CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |
| US-4859669-A | Antiinflammatory and anti-hyperproliferative naphthyridin-4-ones | SCHERING CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |