Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727174 | 1.00 | MAOB (0.44) | MAOBMETAP1RAB9AMEN1KMT2A | |
| SCHEMBL383503 | 0.81 | CA2 (0.52) | MAOBMETAP1RAB9AMEN1KMT2A | |
| SCHEMBL11627151 | 0.77 | CDC25A (0.48) | RAB9AMEN1KMT2ANPC1CA2 | |
| SCHEMBL11773512 | 0.75 | MAOB (0.63) | MAOBRAB9ANPC1PTGS2AURKA | |
| SCHEMBL11773506 | 0.75 | MAOB (0.63) | MAOBRAB9ANPC1PTGS2AURKA | |
| SCHEMBL9727301 | 0.75 | PPOX (0.44) | METAP1RAB9AKDM4ENPC1CA2 | |
| SCHEMBL10591993 | 0.75 | MAOB (0.49) | MAOBKDM4ECA2CA1CA4 | |
| SCHEMBL9727296 | 0.75 | PPOX (0.44) | METAP1RAB9AKDM4ENPC1CA2 | |
| SCHEMBL28996362 | 0.74 | KDM4E (0.61) | MAOBRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL30395765 | 0.74 | KDM4E (0.61) | MAOBRAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144027-A | Cephalosporins, process for producing the same, intermediates thereof and process for producing the intermediates | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-4717767-A | ANTIBIOTICS | TOYAMA CHEMICAL CO., LTD. (JP) | 1988-01-05 | — | — | US | disclosed |
| US-4698352-A | 4-oxo-1,4-dihydronicotinic acid derivatives, salts thereof, and antibacterial agents containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| US-4673738-A | Novel intermediates of cephalosporins and process for producing 7-(substituted or unsubstituted amino)-3-substituted methyl-Δ3 -cephem-4-carboxylic acids | HANDI-PAC INC. (US) | 1987-06-16 | — | — | US | disclosed |
| US-4618606-A | Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4610983-A | N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | disclosed |