Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727301 | 1.00 | PPOX (0.44) | PPOXS100A4METAP1ALDH1A1KDM4E | |
| SCHEMBL20932736 | 0.79 | PPOX (0.48) | PPOXS100A4METAP1KDM4ECA12 | |
| SCHEMBL79617 | 0.78 | S100A4 (0.56) | PPOXS100A4ALDH1A1KDM4ETDP1 | |
| SCHEMBL10587103 | 0.77 | S100A4 (0.54) | PPOXS100A4ALDH1A1KDM4ETDP1 | |
| SCHEMBL4668872 | 0.77 | S100A4 (0.54) | PPOXS100A4ALDH1A1KDM4ETDP1 | |
| SCHEMBL31376098 | 0.77 | S100A4 (0.54) | PPOXS100A4ALDH1A1KDM4ETDP1 | |
| SCHEMBL304550 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL304549 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL17195907 | 0.76 | S100A4 (0.48) | PPOXS100A4METAP1KDM4ETDP1 | |
| SCHEMBL9727176 | 0.75 | MAOB (0.44) | METAP1ALDH1A1KDM4EHPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144027-A | Cephalosporins, process for producing the same, intermediates thereof and process for producing the intermediates | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-4879381-A | ANTIBIOTICS | TOYOMA CHEMICAL COMPANY, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4717767-A | ANTIBIOTICS | TOYAMA CHEMICAL CO., LTD. (JP) | 1988-01-05 | — | — | US | disclosed |
| US-4698352-A | 4-oxo-1,4-dihydronicotinic acid derivatives, salts thereof, and antibacterial agents containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |
| US-4673738-A | Novel intermediates of cephalosporins and process for producing 7-(substituted or unsubstituted amino)-3-substituted methyl-Δ3 -cephem-4-carboxylic acids | HANDI-PAC INC. (US) | 1987-06-16 | — | — | US | disclosed |
| US-4618606-A | Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4610983-A | N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | disclosed |
| US-4489072-A | BACTERICIDE, ANTIBIOTIC | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-12-18 | — | — | US | disclosed |