Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401187 | 0.82 | KMT2A (0.45) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| SCHEMBL16400474 | 0.82 | CA2 (0.45) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| SCHEMBL16409298 | 0.78 | SMN1; SMN2 (0.43) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| SCHEMBL24313467 | 0.78 | MEN1 (0.50) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| SCHEMBL21962249 | 0.77 | CHRNA7 (0.44) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| SCHEMBL28307604 | 0.77 | MKNK1 (0.49) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| Acetic Acid SCHEMBL27869895 | 0.76 | KMT2A (0.43) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| SCHEMBL11677845 | 0.75 | LMNA (0.59) | KMT2AMEN1CHRNA7POLBSMN1; SMN2 | |
| SCHEMBL29347914 | 0.75 | MEN1 (0.51) | KMT2AMEN1CYP2D6CYP2C19CHRNB2 | |
| SCHEMBL1931626 | 0.75 | LMNA (0.59) | KMT2AMEN1CHRNA7POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-5041436-A | 1-arylsulphonyl-2-piperidinone derivatives, process and intermediates for the preparation thereof, their application as antispasmodics and compositions containing them | ROUSSEL UCLAF (FR) | 1991-08-20 | — | — | US | disclosed |
| US-5037822-A | Antispasmodic agent | ROUSSEL-UCLAF (FR) | 1991-08-06 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |