Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401187 | 0.95 | KMT2A (0.45) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| Acetic Acid SCHEMBL27869895 | 0.88 | KMT2A (0.43) | MKNK1CHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL21962249 | 0.83 | CHRNA7 (0.44) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL2626635 | 0.82 | SMN1; SMN2 (0.44) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL17538757 | 0.81 | CHRNB2 (0.46) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL12719203 | 0.79 | ALDH1A1 (0.49) | MKNK1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16400474 | 0.78 | CA2 (0.45) | CHRNB2CHRNA7CHRNA4KMT2AMEN1 | |
| SCHEMBL4725638 | 0.78 | PNMT (0.37) | ENPP2 | |
| SCHEMBL16409298 | 0.78 | SMN1; SMN2 (0.43) | MKNK1CHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL24364104 | 0.77 | ENPP2 (0.36) | KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490708-A | Sulfonamide macrocyclic derivatives, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-106458955-B | Aryl substituted heterocyclyl sulfones | 格吕伦塔尔有限公司 | 2019-07-19 | — | — | CN | disclosed |