Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 3/20 | 0.56 |
| ▸ | WDR5 | P61964 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 2/20 | 0.51 |
| ▸ | FLT4 | P35916 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15313281 | 0.81 | AKR1C4 (0.49) | ALDH1A1ACLYWDR5CCR2 | |
| SCHEMBL6714065 | 0.79 | METAP2 (0.66) | METAP2ALDH1A1ACLYWDR5FLT1 | |
| SCHEMBL492024 | 0.79 | ACLY (0.81) | METAP2ALDH1A1ACLY | |
| SCHEMBL28794509 | 0.77 | AKR1C4 (0.55) | ALDH1A1ACLY | |
| SCHEMBL11028538 | 0.76 | FFAR4 (0.56) | ALDH1A1FLT1FLT4KDRFFAR4 | |
| SCHEMBL6713098 | 0.76 | KDM1A (0.68) | METAP2ALDH1A1ACLYWDR5CCR2 | |
| SCHEMBL12200963 | 0.75 | ACLY (0.78) | METAP2ALDH1A1ACLYWDR5FLT1 | |
| SCHEMBL9164473 | 0.74 | METAP2 (0.85) | METAP2ACLY | |
| SCHEMBL491833 | 0.74 | METAP2 (1.00) | METAP2ALDH1A1ACLYCCR2 | |
| Hydrochloric Acid SCHEMBL7409073 | 0.73 | METAP2 (0.82) | METAP2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132314-A | For administration to mammals, anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | claimed |
| US-5081125-A | Substituted anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-01-14 | — | — | US | claimed |
| US-5132314-A | For administration to mammals, anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5081125-A | Substituted anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| US-5077300-A | Parasiticides | CIBA-GEIGY CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0420804-A2 | Anthelmintic compounds | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |