Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.66 |
| ▸ | FLT1 | P17948 | 4/20 | 0.53 |
| ▸ | FLT4 | P35916 | 4/20 | 0.53 |
| ▸ | KDR | P35968 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.51 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.51 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.51 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925257 | 0.80 | METAP2 (1.00) | METAP2ALDH1A1SLC10A2SLC10A1SLC10A6 | |
| SCHEMBL9727349 | 0.79 | METAP2 (0.59) | METAP2FLT1FLT4KDRALDH1A1 | |
| SCHEMBL1307683 | 0.75 | PRSS12 (0.56) | ACLY | |
| SCHEMBL6811229 | 0.75 | METAP2 (0.58) | METAP2ALDH1A1FFAR4GPR27KDM1A | |
| SCHEMBL7447739 | 0.73 | FFAR4 (0.60) | METAP2ALDH1A1FFAR4 | |
| SCHEMBL6713098 | 0.73 | KDM1A (0.68) | METAP2ALDH1A1WDR5CCR2KDM1A | |
| SCHEMBL492024 | 0.73 | ACLY (0.81) | METAP2ALDH1A1ACLY | |
| SCHEMBL12200963 | 0.72 | ACLY (0.78) | METAP2FLT1FLT4KDRALDH1A1 | |
| SCHEMBL1307192 | 0.72 | MEN1 (0.55) | ALDH1A1 | |
| SCHEMBL5597721 | 0.71 | METAP2 (0.80) | METAP2FLT1FLT4KDRSLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022525-A1 | AMIDE DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 2004-03-18 | — | — | WO | claimed |
| WO-2004022525-A1 | AMIDE DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 2004-03-18 | — | — | WO | disclosed |