Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053440 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL11691006 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL5545202 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL29351158 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL7752251 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL9727529 | 0.72 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL825325 | 0.71 | ALDH1A1 (0.65) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL6864432 | 0.70 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL6629658 | 0.69 | TSHR (0.38) | ALDH1A1HPGDCYP3A4HSD17B10TSHR | |
| SCHEMBL6629756 | 0.69 | CD44 (0.45) | ALDH1A1HPGDCYP3A4HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091502-A | Tetraketone porphyrin monomers and the porphyrin-based polymers thereof | GENERAL PETROCHEMICAL INDUSTRIES LTD (JP) | 1992-02-25 | — | — | US | disclosed |
| US-4908442-A | Tetra ketone porphyrin monomers and the process of preparation thereof | GENERAL PETROCHEMICAL INDUSTRIES, LIMITED (JP) | 1990-03-13 | — | — | US | disclosed |