Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878281 | 0.81 | ALDH1A1 (0.48) | TSHRALDH1A1NR4A2HPGDCYP3A4 | |
| SCHEMBL8878283 | 0.81 | CD44 (0.42) | TSHRALDH1A1NR4A2HPGDCYP3A4 | |
| SCHEMBL10053440 | 0.78 | ALDH1A1 (0.44) | TSHRALDH1A1HPGDCYP3A4KEAP1 | |
| SCHEMBL6629381 | 0.75 | TSHR (0.42) | TSHRALDH1A1NR4A2HPGDCYP3A4 | |
| SCHEMBL30064915 | 0.72 | TSHR (0.52) | TSHRALDH1A1NR4A2HPGDCYP3A4 | |
| SCHEMBL4076360 | 0.72 | TSHR (0.52) | TSHRALDH1A1NR4A2HPGDCYP3A4 | |
| SCHEMBL7915000 | 0.71 | ALDH1A1 (0.48) | TSHRALDH1A1NR4A2HPGDCYP3A4 | |
| SCHEMBL11691006 | 0.69 | ALDH1A1 (0.52) | TSHRALDH1A1HPGDCYP3A4KEAP1 | |
| SCHEMBL9727376 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1NR4A2HPGDCYP3A4 | |
| SCHEMBL6629756 | 0.68 | CD44 (0.45) | TSHRALDH1A1HPGDCYP3A4KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830931-A | DYEING SYNTHETIC HYDROPHOBIC MATERIAL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | claimed |
| US-6833455-B2 | Coloring plastics | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-21 | — | — | US | disclosed |
| EP-1314754-B1 | Bridged Perinones/Quinophtalones | BAYER CHEMICALS AG (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-20030139498-A1 | Bridged perinones/quinophthalones | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | US | disclosed |
| EP-1118640-B1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| EP-1314754-A1 | Bridged Perinones/Quinophtalones | Bayer Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | disclosed |
| EP-0827986-B1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-0780444-B1 | Process to manufacture polycyclic compounds | BAYER AG (DE) | 2001-09-05 | — | — | EP | disclosed |
| EP-1118640-A1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| US-5955614-A | Bridged perinones/quinophthalones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5830931-A | DYEING SYNTHETIC HYDROPHOBIC MATERIAL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0827986-A2 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 1998-03-11 | — | — | EP | disclosed |
| EP-0780444-A2 | Process to manufacture polycyclic compounds | BAYER AG (DE) | 1997-06-25 | — | — | EP | disclosed |
| US-5621027-A | Dyestuffs for bulk dyeing plastics | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0683212-A1 | New dyes for the bulk dyeing of synthetic materials | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |
| US-4024144-A | SULFONIC ACID GROUPS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139498-A1 | Bridged perinones/quinophthalones | CYP11B1, CYP1B1, CYP11B2 | TSHR 3697/4885ALDH1A1 310/4885NR4A2 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.