SCHEMBL9852839

CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	17/20	0.59

▸	NPBWR1	P48145	1/20	0.59

▸	NPFFR1	Q9GZQ6	1/20	0.56

▸	GLP1R	P43220	2/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30598017	0.90	KISS1R (0.58)	KISS1RGLP1R
Tauramamide SCHEMBL29625500	0.89	NPBWR1 (0.64)	KISS1RNPBWR1NPFFR1GLP1R
SCHEMBL9852713	0.88	IL1RN (0.53)	KISS1R
SCHEMBL9727453	0.88	KISS1R (0.61)	KISS1RNPBWR1NPFFR1
SCHEMBL30518038	0.88	NPBWR1 (0.61)	KISS1RNPBWR1GLP1R
SCHEMBL9631356	0.87	C5AR1 (0.62)	KISS1R
SCHEMBL30845372	0.85	KISS1R (0.71)	KISS1RNPBWR1NPFFR1GLP1R
SCHEMBL31439367	0.85	NPBWR1 (0.65)	NPBWR1
SCHEMBL30518069	0.84	C5AR1 (0.59)	KISS1RNPBWR1
SCHEMBL29683405	0.84	C5AR1 (0.56)	KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0417454-A2	Reduced size LHRH analogs	ABBOTT LABORATORIES (US)	1991-03-20	—	—	EP	disclosed
EP-0328089-A2	Reduced size LHRH analogs	ABBOTT LABORATORIES (US)	1989-08-16	—	—	EP	disclosed