Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455707 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10TSHRFAAH | |
| SCHEMBL28728927 | 0.77 | DDAH1 (0.34) | TSHRMAPTHPGDTDP1CHRM1 | |
| SCHEMBL262227 | 0.76 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRFAAH | |
| SCHEMBL11918310 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10TSHRFAAH | |
| SCHEMBL620326 | 0.71 | FFAR3 (0.42) | ALDH1A1TDP1CHRM1CHRM3 | |
| Ethylmalonate SCHEMBL10702049 | 0.70 | FFAR3 (0.47) | ALDH1A1TDP1CHRM1CHRM3 | |
| SCHEMBL515965 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TSHRSMN1; SMN2MAPTTDP1 | |
| SCHEMBL1171608 | 0.69 | LMNA (0.33) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL18668989 | 0.69 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10TSHRFAAH | |
| SCHEMBL10454564 | 0.69 | SMN1; SMN2 (0.34) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103006-A | Calcium channel activator; inotropic agent | E. R. SQUIBB & SONS, INC. (US) | 1992-04-07 | — | — | US | disclosed |