SCHEMBL9727500

SCHEMBL9727500

CCC(OC(C)=O)C(=O)CC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
TSHR P16473 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 2/20 0.35
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
LDHA P00338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4611990 0.81 ALDH1A1 (0.39) TSHRALDH1A1
SCHEMBL10455855 0.78 TSHR (0.44) ALOX15TSHRSMN1; SMN2LMNAHDAC3
SCHEMBL15196486 0.78 TSHR (0.42) ALOX15TSHRSMN1; SMN2LMNAHDAC1
SCHEMBL10711004 0.78 TSHR (0.42) ALOX15TSHRSMN1; SMN2LMNAHDAC1
SCHEMBL4464866 0.78 TSHR (0.42) ALOX15TSHRSMN1; SMN2LMNAHDAC1
SCHEMBL11384253 0.77 TSHR (0.37) ALOX15TSHRSMN1; SMN2LMNACHRM2
SCHEMBL28564952 0.77 TSHR (0.37) ALOX15TSHRSMN1; SMN2LMNACHRM2
SCHEMBL5744405 0.77 TSHR (0.37) TSHRSMN1; SMN2HDAC3HDAC1HDAC2
SCHEMBL23175068 0.75 TSHR (0.36) TSHRSMN1; SMN2HDAC3HDAC1HDAC2
SCHEMBL21292116 0.75 LDHA (0.32) LDHASRRFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5103006-A Calcium channel activator; inotropic agent E. R. SQUIBB & SONS, INC. (US) 1992-04-07 US disclosed