Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935578 | 0.86 | XDH (0.40) | CYP3A4ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9778188 | 0.81 | CYP3A4 (0.58) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL29220195 | 0.80 | CYP3A4 (0.53) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL7989898 | 0.80 | CYP3A4 (0.57) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL16874354 | 0.76 | GABRA1 (0.46) | ALDH1A1TSHRTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8667888 | 0.75 | PTPN1 (0.44) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL8100905 | 0.72 | CYP3A4 (0.61) | CYP3A4ALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL9717642 | 0.72 | CYP3A4 (0.69) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL9227768 | 0.72 | ALDH1A1 (0.43) | CYP3A4ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL9346999 | 0.72 | CYP3A4 (0.46) | CYP3A4ALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084579-A | Vitamin A deficiency and retinoid activity | L'OREAL (FR) | 1992-01-28 | — | — | US | disclosed |
| US-5075331-A | For skin disorders | L'OREAL (FR) | 1991-12-24 | — | — | US | disclosed |