SCHEMBL9727630

SCHEMBL9727630

O=C(O)[C@@H]1CCCN1C(=O)C(F)c1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ACE P12821 4/20 0.47
LTA4H P09960 5/20 0.46
ITGB3 P05106 1/20 0.43
ITGB1 P05556 1/20 0.43
ITGAV P06756 1/20 0.43
ITGA5 P08648 1/20 0.43
ITGA4 P13612 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9727508 0.85 ALDH1A1 (0.45) ALDH1A1ACE
SCHEMBL9727391 0.79 MEN1 (0.47) ALDH1A1SMN1; SMN2
SCHEMBL1308046 0.74 RAB9A (0.58) ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV
SCHEMBL3718797 0.73 ACE (0.51) ACELTA4H
SCHEMBL6437305 0.72 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2ACELTA4HITGB3
SCHEMBL1308616 0.72 TSHR (0.55) ALDH1A1SMN1; SMN2ITGB3ITGB1ITGAV
SCHEMBL6437308 0.72 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2ACELTA4HITGB3
SCHEMBL9727523 0.72 ALDH1A1 (0.46) ALDH1A1ACE
SCHEMBL3238628 0.71 DPP4 (0.67) ALDH1A1SMN1; SMN2ACELTA4HITGB3
SCHEMBL9362237 0.71 ACE (0.55) ALDH1A1SMN1; SMN2ACELTA4HITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142065-A Intermediates for herbicides, fungicides, miticides and insecticides BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-5091537-A Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4985063-A INSECTICIDES, MITICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed