SCHEMBL9727508

SCHEMBL9727508

COC(=O)C1CCCN1C(=O)C(F)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
ALOX5 P09917 1/20 0.44
PEPD P12955 3/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
PDK2 Q15119 1/20 0.42
XPNPEP1 Q9NQW7 2/20 0.42
ACE P12821 1/20 0.42
GAA P10253 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
OPRL1 P41146 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9727523 0.87 ALDH1A1 (0.46) ALDH1A1ALOX5PEPDCYP1A2CYP3A4
SCHEMBL9727630 0.85 ALDH1A1 (0.48) ALDH1A1ACE
SCHEMBL9727391 0.84 MEN1 (0.47) ALDH1A1GAAOPRL1
SCHEMBL9727470 0.78 PEPD (0.43) ALDH1A1ALOX5PEPDPDK2XPNPEP1
SCHEMBL9727329 0.76 ALDH1A1 (0.52) ALDH1A1ALOX5PEPDCYP1A2CYP3A4
SCHEMBL9727475 0.74 ALDH1A1 (0.52) ALDH1A1ALOX5PEPDCYP1A2CYP3A4
SCHEMBL18621630 0.73 TAS1R3 (0.50) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22209536 0.73 TAS1R3 (0.50) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL15614468 0.73 CNR2 (0.51) ALOX5PDK2ACECNR1CNR2
SCHEMBL9727278 0.72 TSHR (0.54) ALDH1A1ALOX5PEPDXPNPEP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142065-A Intermediates for herbicides, fungicides, miticides and insecticides BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-5091537-A Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4985063-A INSECTICIDES, MITICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed