Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594508 | 0.80 | KMT2A (0.44) | KMT2AMEN1GAATSHRCYP3A4 | |
| SCHEMBL9727673 | 0.78 | KMT2A (0.43) | KMT2AMEN1GAATSHRCYP3A4 | |
| SCHEMBL9727635 | 0.74 | GAA (0.46) | KMT2AMEN1GAATP53 | |
| SCHEMBL10879279 | 0.72 | GAA (0.50) | KMT2AMEN1GAATSHRCYP3A4 | |
| SCHEMBL7380549 | 0.71 | PKM (0.62) | KMT2AMEN1GAACYP3A4CYP2C9 | |
| SCHEMBL14529339 | 0.70 | GAA (0.51) | KMT2AMEN1GAATP53CRHBP | |
| SCHEMBL9727395 | 0.70 | KMT2A (0.42) | KMT2AMEN1GAATSHRCYP3A4 | |
| SCHEMBL10876708 | 0.70 | CYP2C9 (0.49) | KMT2AMEN1GAATSHRCYP3A4 | |
| SCHEMBL10877910 | 0.70 | CHRM4 (0.53) | KMT2AMEN1TSHRCYP3A4CYP2C9 | |
| SCHEMBL10884111 | 0.70 | KMT2A (0.51) | KMT2AMEN1GAATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |