Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594508 | 0.93 | KMT2A (0.44) | KMT2AMEN1GAATP53CRHBP | |
| SCHEMBL9727641 | 0.78 | KMT2A (0.47) | KMT2AMEN1GAATP53CRHBP | |
| SCHEMBL9727670 | 0.78 | TP53 (0.41) | KMT2AMEN1GAATP53MAPK1 | |
| SCHEMBL9799573 | 0.69 | TP53 (0.46) | KMT2AMEN1GAATP53 | |
| SCHEMBL11845023 | 0.69 | HTR6 (0.58) | KMT2ATDP1 | |
| SCHEMBL10879279 | 0.68 | GAA (0.50) | KMT2AMEN1GAACRHBPCRHR2 | |
| SCHEMBL9724223 | 0.67 | CA12 (0.44) | TP53MAPK1CYP3A4TSHRTDP1 | |
| SCHEMBL7153352 | 0.66 | TDP1 (0.44) | KMT2AMEN1GAATP53MAPK1 | |
| SCHEMBL7380549 | 0.66 | PKM (0.62) | KMT2AMEN1GAATP53CYP3A4 | |
| SCHEMBL9727395 | 0.66 | KMT2A (0.42) | KMT2AMEN1GAATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| EP-0335758-A2 | Derivatives of 1-arylsulfonyl-2-pyrolidinone, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-10-04 | — | — | EP | disclosed |