SCHEMBL972790

SCHEMBL972790

Cc1cc(/N=N/c2ccccc2)c(N)cc1N

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.67
▸ KMT2A Q03164 8/20 0.67
▸ MAPT P10636 7/20 0.67
▸ NPC1 O15118 5/20 0.67
▸ RAB9A P51151 4/20 0.67
▸ USP2 O75604 2/20 0.67
▸ KDM4E B2RXH2 2/20 0.67
▸ BLM P54132 1/20 0.67
▸ PHLPP2 Q6ZVD8 1/20 0.58
▸ MAPK1 P28482 7/20 0.56
▸ TDP1 Q9NUW8 6/20 0.56
▸ CYP3A4 P08684 4/20 0.56
▸ SMN1; SMN2 Q16637 4/20 0.56
▸ TSHR P16473 3/20 0.56
▸ TP53 P04637 2/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ L3MBTL1 Q9Y468 3/20 0.49
▸ PKM P14618 2/20 0.49
▸ ATM Q13315 1/20 0.49
▸ TRPA1 O75762 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL972791 1.00 MEN1 (0.67) MEN1KMT2AMAPTNPC1RAB9A
Hydrochloric Acid SCHEMBL6254664 0.98 MEN1 (0.65) MEN1KMT2AMAPTNPC1RAB9A
Hydrochloric Acid SCHEMBL6259167 0.98 MEN1 (0.65) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11216129 0.91 MAPK1 (0.58) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL2610133 0.89 MEN1 (0.57) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11062514 0.89 MEN1 (0.57) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL12157598 0.87 MEN1 (0.60) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11236335 0.85 NPC1 (0.72) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11236338 0.85 NPC1 (0.72) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11239443 0.84 BRD4 (0.55) MEN1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110020251-A1 Ultraviolet-Absorbing Compounds AVOCA LLC 2011-01-27 — — US claimed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 — — US disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 — — US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 — — US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 — — US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 — — US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 — — US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 — — US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 — — US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 — — US disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 — — US disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 — — US disclosed
WO-2011084803-A2 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-07-14 — — WO disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 — — US disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 — — US disclosed
US-20110020251-A1 Ultraviolet-Absorbing Compounds AVOCA LLC 2011-01-27 — — US disclosed
US-4323682-A BLEACHING CATALYSTS CIBA GEIGY AG (CH) 1982-04-06 — — US disclosed
US-4202698-A DYE BLEACH CATALYSTS CIBA-GEIGY AG (CH) 1980-05-13 — — US disclosed
US-4151213-A REACTION PRODUCT OF TRANSITION METAL HALIDE WITH SILVER NITRITE FOR OXIDIZING ALKYLAROMATICS STANDARD OIL COMPANY (INDIANA) (US) 1979-04-24 — — US disclosed
US-4042531-A TRANSITION METAL HALIDE AND SILVER NITRITE STANDARD OIL COMPANY (INDIANA) (US) 1977-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020251-A1 Ultraviolet-Absorbing Compounds UFM1, UHRF1, CUTA MEN1 284/4885KMT2A 756/4885MAPT 322/4885
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MEN1 3187/4885KMT2A 1622/4885MAPT 2715/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MEN1 3187/4885KMT2A 1622/4885MAPT 2715/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MEN1 3187/4885KMT2A 1622/4885MAPT 2715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback