SCHEMBL972795

SCHEMBL972795

C[SiH](CO)O[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2409742 0.73
SCHEMBL508431 0.72
Ethylene Glycol SCHEMBL5320374 0.71 ALDH1A1 (0.30)
SCHEMBL51902 0.69
SCHEMBL1889664 0.69
Alcohol SCHEMBL11060248 0.69
Ethylene Glycol SCHEMBL340266 0.69
SCHEMBL17227923 0.69
SCHEMBL51578 0.67
SCHEMBL9576213 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1633275-B1 RETICULATED ELASTOMERIC MATRICES, THEIR MANUFACTURE AND USE IN IMPLANTABLE DEVICES BIOMERIX CORP (US) 2017-11-29 EP disclosed
US-8337487-B2 Reticulated elastomeric matrices, their manufacture and use in implantable devices BIOMERIX CORPORATION (US) 2012-12-25 US disclosed
US-20110184530-A1 High performance reticulated elastomeric matrix preparation, properties, reinforcement, and use in surgical devices, tissue augmentation and/or tissue repair BIOMERIX CORPORATION (US) 2011-07-28 US disclosed
US-20110014289-A1 Reticulated Elastomeric Matrices, Their Manufacture and Use in Implantable Devices BIOMERIX CORPORATION (US) 2011-01-20 US disclosed
US-20100318108-A1 COMPOSITE MESH DEVICES AND METHODS FOR SOFT TISSUE REPAIR BIOMERIX CORPORATION (US) 2010-12-16 US disclosed
US-20100249913-A1 Reticulated elastomeric matrices, their manufacture and use in implantable devices BIOMERIX CORPORATION (US) 2010-09-30 US disclosed
US-7803395-B2 Reticulated elastomeric matrices, their manufacture and use in implantable devices BIOMERIX CORPORATION (US) 2010-09-28 US disclosed
WO-2010088699-A2 COMPOSITE MESH DEVICES AND METHODS FOR SOFT TISSUE REPAIR BIOMERIX CORPORATION (US) 2010-08-05 WO disclosed
US-7763077-B2 Repair of spinal annular defects and annulo-nucleoplasty regeneration BIOMERIX CORPORATION (US) 2010-07-27 US disclosed
EP-2029108-A2 HIGH PERFORMANCE RETICULATED ELASTOMERIC MATRIX Biomerix Corporation (US) 2009-03-04 EP disclosed
EP-1553899-A2 METHOD AND SYSTEM FOR INTRAVESICULAR DELIVERY OF THERAPEUTIC AGENTS The Biomerix Corporation (US) 2005-07-20 EP disclosed
US-20050149046-A1 Repair of spinal annular defects and annulo-nucleoplasty regeneration BIOMERIX CORPORATION, THE 2005-07-07 US disclosed
US-20050043816-A1 Reticulated elastomeric matrices, their manufacture and use in implantable devices DSM IP ASSETS B.V. (NL) 2005-02-24 US disclosed
US-20050043585-A1 Reticulated elastomeric matrices, their manufacture and use in implantable devices BIOMERIX CORPORATION 2005-02-24 US disclosed
US-20040260272-A1 Method and system for intravesicular delivery of therapeutic agents BIOMERIX CORPORATION, THE 2004-12-23 US disclosed
WO-2004103208-A2 MANUFACTURE AND USE OF IMPLANTABLE RETICULATED ELASTOMERIC MATRICES BIOMERIX CORPORATION (US) 2004-12-02 WO disclosed
WO-2004078023-A2 ANEURYSM TREATMENT DEVICES AND METHODS THE BIOMERIX CORPORATION (US) 2004-09-16 WO disclosed
US-20040167597-A1 Aneurysm treatment devices and methods BIOMERIX CORPORATION, THE 2004-08-26 US disclosed
WO-2004062531-A1 RETICULATED ELASTOMERIC MATRICES, THEIR MANUFACTURE AND USE IN IMPLANTABLE DEVICES BIOMERIX CORPORATION (US) 2004-07-29 WO disclosed
WO-2004037318-A2 METHOD AND SYSTEM FOR INTRAVESICULAR DELIVERY OF THERAPEUTIC AGENTS THE BIOMERIX CORPORATION (US) 2004-05-06 WO disclosed