Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697530 | 0.80 | BACE1 (0.60) | HDAC4HDAC8MAOBSMN1; SMN2HPGD | |
| SCHEMBL1471565 | 0.78 | MAPT (0.46) | MAOBNOTUMSMN1; SMN2HPGDKDM4E | |
| SCHEMBL9850097 | 0.77 | NCOA1 (0.48) | HDAC4HDAC8MAOBGAANOTUM | |
| SCHEMBL25835140 | 0.76 | KDM4E (0.64) | HDAC4HDAC8MAOBGAANOTUM | |
| SCHEMBL196765 | 0.74 | CYP3A4 (0.73) | HDAC4HDAC8MAOBGAANOTUM | |
| SCHEMBL29489425 | 0.74 | CYP3A4 (0.73) | HDAC4HDAC8MAOBGAANOTUM | |
| SCHEMBL29242287 | 0.74 | KMO (0.42) | HDAC4HDAC8NOTUMSMN1; SMN2ALDH1A1 | |
| SCHEMBL3671037 | 0.73 | GAA (0.50) | HDAC4HDAC8GAANOTUMKDM4E | |
| SCHEMBL3023333 | 0.73 | GABRP (0.45) | NOTUMSMN1; SMN2BRD4TP53NPC1 | |
| SCHEMBL1471693 | 0.73 | GABRP (0.45) | MAOBSMN1; SMN2CYP3A4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140013-A | Shelf life; polymerization inhibition; nontoxic; side effects reduction | UNIVERSITE LAVAL (CA) | 1992-08-18 | — | — | US | disclosed |
| WO-1991008775-A2 | MALEIC ANHYDRIDE DERIVATIVES USED AS CONJUGATION AGENTS OF ANTI-TUMOR AGENTS ON DESIRED CARRIERS | UNIVERSITE LAVAL (CA) | 1991-06-27 | — | — | WO | disclosed |