Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | DRD5 | P21918 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727711 | 0.93 | CHRM2 (0.75) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9727789 | 0.91 | CHRM2 (0.73) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9675937 | 0.88 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL11814972 | 0.88 | LMNA (0.68) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL9676066 | 0.88 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL11821921 | 0.87 | LMNA (0.70) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9673821 | 0.87 | CHRM2 (0.51) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL10517009 | 0.86 | CHRM2 (0.66) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9674213 | 0.85 | CHRM2 (0.49) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL10515360 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175158-A | CONDENSED DIAZEPINONES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | DR. KARL THOMAE, GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0312895-A2 | Condensed diazepinones, process for their preparation and medicament containing them | Dr. Karl Thomae GmbH (DE) | 1989-04-26 | — | — | EP | disclosed |