Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818531 | 0.86 | ALDH1A1 (0.77) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL9728720 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL9818510 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL5457277 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL311564 | 0.79 | HPGD (0.62) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL29746319 | 0.79 | HPGD (0.62) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL5455495 | 0.79 | ALDH1A1 (0.72) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL5456687 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL9729071 | 0.77 | CA1 (0.59) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL13167002 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |