Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116500 | 0.96 | HRH3 (0.38) | CYP19A1HRH3IDO1 | |
| SCHEMBL4382430 | 0.89 | CTSK (0.33) | — | |
| SCHEMBL650316 | 0.86 | PPARG (0.38) | HRH3SIGMAR1PPARGPPARADRD4 | |
| SCHEMBL8114784 | 0.86 | CYP19A1 (0.41) | CYP19A1SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL8118972 | 0.86 | HMOX1 (0.34) | SIGMAR1 | |
| SCHEMBL8114437 | 0.83 | CYP19A1 (0.34) | CYP19A1HRH3IDO1HPGDSIGMAR1 | |
| SCHEMBL8794072 | 0.83 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL10743482 | 0.82 | HTR2A (0.42) | HRH3HPGDSIGMAR1 | |
| SCHEMBL7971454 | 0.82 | TRPA1 (0.40) | CYP19A1HRH3GRIK1 | |
| SCHEMBL4376567 | 0.82 | LMNA (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597088-B1 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INST NAT SANTE RECH MED (FR) | 2000-12-06 | — | — | EP | claimed |