Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728502 | 0.85 | KMT2A (0.64) | ALDH1A1HPGDALOX12POLBCYP1A2 | |
| SCHEMBL9728489 | 0.84 | ALDH1A1 (0.62) | ALDH1A1ALOX12POLBCYP1A2CYP2C19 | |
| SCHEMBL9818475 | 0.82 | LMNA (0.56) | ALDH1A1HPGDALOX12POLBSMN1; SMN2 | |
| SCHEMBL5458272 | 0.81 | ALDH1A1 (0.75) | ALDH1A1HPGDALOX12POLBCYP1A2 | |
| SCHEMBL9728776 | 0.79 | ALDH1A1 (0.67) | ALDH1A1ALOX12POLBCYP1A2CYP3A4 | |
| SCHEMBL9818531 | 0.77 | ALDH1A1 (0.77) | ALDH1A1HPGDALOX12POLBSMN1; SMN2 | |
| SCHEMBL5458075 | 0.75 | ALDH1A1 (0.67) | ALDH1A1HPGDALOX12POLBSMN1; SMN2 | |
| SCHEMBL3397939 | 0.75 | NPC1 (0.60) | ALDH1A1HPGDALOX12POLBCYP1A2 | |
| SCHEMBL28984805 | 0.74 | SETDB1 (0.49) | ALDH1A1HPGDLMNAMAPTKDM4E | |
| SCHEMBL28261835 | 0.74 | HPGD (1.00) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |