SCHEMBL972849

SCHEMBL972849

C=CC(=C)C.CC(C)=CBr

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
TSHR P16473 2/20 0.67
TP53 P04637 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8610971 0.86
Iodomethane SCHEMBL9065550 0.82
SCHEMBL20661241 0.82 ALDH1A1 (1.00) ALDH1A1TSHRTP53
SCHEMBL14855 0.82
SCHEMBL1331930 0.82
SCHEMBL322832 0.82 ALDH1A1 (1.00) ALDH1A1TSHRTP53
SCHEMBL5048665 0.79 ALDH1A1 (0.77) ALDH1A1TSHRTP53
SCHEMBL4421781 0.78 ALDH1A1 (0.91) ALDH1A1TSHRTP53
Ethylene SCHEMBL8752751 0.78
Bromide SCHEMBL8198603 0.78 ALDH1A1 (0.91) ALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105237-A1 ORGANIC FILLERS WITH THIOETHER LINKAGES SUNCOAL INDUSTRIES GMBH (DE) 2024-05-23 WO claimed
EP-4341104-A1 ORGANOSILANE-MODIFIED ORGANIC FILLERS AND RUBBER COMPOSITIONS CONTAINING SAID FILLERS SunCoal Industries GmbH (DE) 2024-03-27 EP claimed
EP-4341342-A1 SURFACE-MODIFIED ORGANIC FILLERS AND RUBBER COMPOSITIONS CONTAINING SAME SunCoal Industries GmbH (DE) 2024-03-27 EP claimed
EP-3122802-B1 AN ADDITIVE FOR PLASTICS COMPRISING VEGETAL FIBER GANDUXE ALEJANDRO LBAN (ES) 2023-06-28 EP claimed
EP-3181571-B1 SILICON-CONTAINING AZODICARBOXAMIDES, THEIR PREPARATION AND USE EVONIK DEGUSSA GMBH (DE) 2019-07-24 EP claimed
US-10150265-B1 Method of manufacturing a synthetic skin and tissue model UNIVERSITY OF SOUTH FLORIDA (US) 2018-12-11 US claimed
US-9981995-B2 Azocarbonyl-functionalized silanes EVONIK DEGUSSA GMBH (DE) 2018-05-29 US claimed
EP-2937351-B1 AZOCARBONYL-FUNCTIONALIZED SILANES EVONIK DEGUSSA GMBH (DE) 2017-11-15 EP claimed
US-20170174712-A1 Silicon-containing azodicarboxamides, their preparation and use EVOINIK DEGUSSA GmbH (DE) 2017-06-22 US claimed
US-9514658-B1 Synthetic skin and tissue model UNIVERSITY OF SOUTH FLORIDA (US) 2016-12-06 US claimed
EP-2508559-A1 Rubber mixtures Evonik Degussa GmbH (DE) 2012-10-10 EP claimed
US-20120251751-A1 RUBBER MIXTURES EVONIK DEGUSSA GMBH (DE) 2012-10-04 US claimed
EP-0804700-B1 ELONGATED FUEL AND VAPOR TUBE HAVING MULTIPLE LAYERS AND METHOD OF MAKING THE SAME ITT MFG ENTERPRISES INC (US) 2002-05-15 EP claimed
EP-1186818-A1 Elongated fuel and vapor tube having multiple layers and method of making the same ITT MANUFACTURING ENTERPRISES, INC. (US) 2002-03-13 EP claimed
US-6028137-A Elastomeric compounds incorporating silicon-treated carbon blacks CABOT CORPORATION (US) 2000-02-22 US claimed
EP-0792216-B1 PROFILED MOTOR VEHICLE SEAL BAEDJE K H METEOR GUMMIWERKE (DE) 1999-06-30 EP claimed
EP-0804700-A1 ELONGATED FUEL AND VAPOR TUBE HAVING MULTIPLE LAYERS AND METHOD OF MAKING THE SAME ITT MANUFACTURING ENTERPRISES, INC. (US) 1997-11-05 EP claimed
US-5566720-A Elongated fuel and vapor tube having multiple layers and method of making the same ITT CORPORATION (US) 1996-10-22 US claimed
WO-1996021820-A1 ELONGATED FUEL AND VAPOR TUBE HAVING MULTIPLE LAYERS AND METHOD OF MAKING THE SAME ITT MANUFACTURING ENTERPRISES, INC. (US) 1996-07-18 WO claimed
US-4842024-A INNER ELASTOMER PLY, MIDDLE THERMOPLASTIC PLY, OUTER ELASTOMER PLY, TEXTILE REINFORCEMENTS HARVARD INDUSTRIES, INC. (US) 1989-06-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170174712-A1 Silicon-containing azodicarboxamides, their preparation and use SOS1, CRY1, PYCARD ALDH1A1 2975/4885TSHR 4535/4885TP53 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.