Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CCR6 | P51684 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728074 | 0.89 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL9818510 | 0.88 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL9728573 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL9729151 | 0.86 | KMT2A (0.61) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL9728350 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL9729024 | 0.86 | ALDH1A1 (0.80) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL11079536 | 0.86 | PDCD1 (0.72) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL9728096 | 0.84 | EPHX1 (0.66) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL9818531 | 0.83 | ALDH1A1 (0.77) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL14096476 | 0.83 | RAB9A (1.00) | ALDH1A1KDM4EMAPTALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |