Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 10/20 | 0.51 |
| ▸ | FABP3 | P05413 | 2/20 | 0.51 |
| ▸ | FABP2 | P12104 | 2/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 3/20 | 0.46 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11485444 | 0.98 | LMNA (0.61) | LMNANPSR1MEN1CYP3A4TSHR | |
| SCHEMBL9433064 | 0.84 | LMNA (0.44) | LMNANPSR1MEN1CYP3A4TSHR | |
| SCHEMBL11472500 | 0.82 | LMNA (0.65) | LMNANPSR1MEN1CYP3A4TSHR | |
| SCHEMBL5208861 | 0.80 | LMNA (0.62) | LMNANPSR1MEN1CYP3A4TSHR | |
| SCHEMBL2531253 | 0.80 | LMNA (0.68) | LMNANPSR1MEN1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL28256990 | 0.80 | LMNA (0.62) | LMNANPSR1MEN1CYP3A4TSHR | |
| SCHEMBL388034 | 0.78 | MAPT (0.55) | LMNAMEN1TSHRKMT2AEDNRA | |
| SCHEMBL4095819 | 0.78 | LMNA (0.44) | LMNANPSR1MEN1CYP3A4TSHR | |
| SCHEMBL17908025 | 0.77 | LMNA (1.00) | LMNANPSR1MEN1CYP3A4TSHR | |
| SCHEMBL16346833 | 0.77 | LMNA (0.64) | LMNANPSR1MEN1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960400-B | Sulfamoylthiophene amide derivatives and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-106279167-B | Matrine compound derivative and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2018-11-13 | — | — | CN | disclosed |
| CN-107298646-A | A kind of preparation method of noradrenalin | 江西永通科技股份有限公司 | 2017-10-27 | — | — | CN | disclosed |
| CN-107141308-A | A kind of preparation method of tenoxicam | 江西永通科技股份有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-106279167-A | Matrine compound derivative and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2017-01-04 | — | — | CN | disclosed |
| CN-102731488-A | Benzimidazole derivatives, preparation method thereof, pharmaceutical composition thereof and application thereof | INST MATERIA MEDICA CAMS | 2012-10-17 | — | — | CN | disclosed |
| CN-1671386-A | Substituted anilinic piperidines as MCH selective antagonists | LUNDBECK & CO AS H (DK) | 2005-09-21 | — | — | CN | disclosed |
| US-5138072-A | Process for the preparation of 5-chloro-3-chlorosulphonyl-2-thiophenecarboxylic acid esters | HAFSLUND NYCOMED PHARMA AKTIENGESELLSCHAFT (AT) | 1992-08-11 | — | — | US | disclosed |
| US-4028373-A | ARTIFICIAL SWEETNERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-06-07 | — | — | US | disclosed |