Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729300 | 0.83 | AOC3 (0.41) | ALDH1A1AOC3LMNASCN8ASMN1; SMN2 | |
| SCHEMBL9729205 | 0.81 | ALDH1A1 (0.46) | ALDH1A1AOC3LMNASCN8ASMN1; SMN2 | |
| SCHEMBL9729471 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TDP1KDM4EGAAAOC3 | |
| SCHEMBL9729157 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1AOC3LMNASMN1; SMN2CHRM2 | |
| SCHEMBL9728882 | 0.78 | HPGD (0.49) | ALDH1A1GAAAOC3LMNACHRM2 | |
| SCHEMBL9728901 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EAOC3LMNACHRM2 | |
| SCHEMBL9729228 | 0.76 | AOC3 (0.50) | ALDH1A1TDP1KDM4EAOC3LMNA | |
| SCHEMBL4083083 | 0.76 | AOC3 (0.53) | ALDH1A1KDM4EAOC3LMNACHRM2 | |
| SCHEMBL9729078 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EAOC3LMNASMN1; SMN2 | |
| SCHEMBL9729241 | 0.76 | AOC3 (0.46) | ALDH1A1KDM4EAOC3LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803200-A | SHIPPING FEVER SYNDROME | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-07 | — | — | US | claimed |
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |
| US-4803200-A | SHIPPING FEVER SYNDROME | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-07 | — | — | US | disclosed |