Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729081 | 1.00 | SMPD3 (0.48) | SMPD3IRAK4KDM4EALDH1A1LMNA | |
| SCHEMBL9728877 | 0.79 | PDE2A (0.46) | HSD11B1 | |
| SCHEMBL4940332 | 0.77 | IRAK4 (0.56) | SMPD3IRAK4KDM4EALDH1A1LMNA | |
| SCHEMBL10042194 | 0.75 | HTT (0.58) | SMPD3IRAK4KDM4EALDH1A1LMNA | |
| SCHEMBL309036 | 0.75 | IRAK4 (0.58) | SMPD3IRAK4KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL31474423 | 0.74 | IRAK4 (0.57) | SMPD3IRAK4KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30152392 | 0.74 | IRAK4 (0.57) | SMPD3IRAK4KDM4EALDH1A1LMNA | |
| SCHEMBL9728973 | 0.73 | CLK4 (0.61) | IRAK4KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9728968 | 0.73 | CLK4 (0.61) | IRAK4KDM4EALDH1A1HPGDHTT | |
| SCHEMBL30579396 | 0.73 | IRAK4 (0.53) | SMPD3IRAK4KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169850-A | Neurotropic or hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | disclosed |