Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.56 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30579396 | 0.85 | IRAK4 (0.53) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| SCHEMBL9728912 | 0.84 | HSD17B10 (0.52) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| SCHEMBL10042194 | 0.82 | HTT (0.58) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| SCHEMBL309036 | 0.82 | IRAK4 (0.58) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL31474423 | 0.80 | IRAK4 (0.57) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL30152392 | 0.80 | IRAK4 (0.57) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| SCHEMBL17848939 | 0.79 | IRAK4 (0.46) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| SCHEMBL17848875 | 0.79 | ALDH1A1 (0.47) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| SCHEMBL946897 | 0.79 | IRAK4 (0.68) | IRAK4SMPD3HTTSMN1; SMN2NPC1 | |
| SCHEMBL309358 | 0.79 | HSD11B1 (0.57) | IRAK4SMPD3HTTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945378-B | Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof | 休斯敦大学体系 | 2024-11-19 | — | — | CN | disclosed |
| US-20080221129-A1 | New compounds | BIOVITRUM AB (PUBL) (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221129-A1 | New compounds | SCD, SCD5, FASN | IRAK4 1256/4885SMPD3 482/4885HTT 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.